serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
25453
UniProt ID:
Q07731
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables protein homodimerization activity and signaling receptor binding activity. Involved in several processes, including negative regulation of apoptotic process; regulation of cytokine production; and regulation of morphogenesis of an epithelium. Located in extracellular space. Part of receptor complex. Used to study alcohol dependence; alcohol use disorder; brain disease (multiple); and hyperprolactinemia. Biomarker of several diseases, including alcohol use disorder; irritable bowel syndrome; middle cerebral artery infarction; neuropathy (multiple); and nicotine dependence. Human ortholog(s) of this gene implicated in several diseases, including Hirschsprung's disease; Parkinsonism; anxiety disorder; depressive disorder; and heroin dependence. Orthologous to human GDNF (glial cell derived neurotrophic factor).
