| Detection range: | 0.156-10ng/mL |
| Sensitivity: | 0.069ng/mL |
| Type: | Traditional GKN1 ELISA kit |
| Synonyms: | CA11; AMP18; BRICD1; FOV; Foveolin; 18 kDa antrum mucosa protein |
| Species: | Rat |
| Sample type: | serum, plasma, tissue homogenates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 297418 |
| UniProt ID: | Gkn1 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Enables growth hormone secretagogue receptor activity and peptide hormone binding activity. Involved in several processes, including cellular response to insulin-like growth factor stimulus; regulation of digestive system process; and regulation of secretion by cell. Acts upstream of or within negative regulation of insulin secretion. Is active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and synaptic membrane. Used to study middle cerebral artery infarction. Biomarker of isolated growth hormone deficiency; multiple endocrine neoplasia; obstructive sleep apnea; status epilepticus; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in obesity. Orthologous to human GHSR (growth hormone secretagogue receptor).
