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Gls
| Detection range: | 0.312-20ng/mL |
| Sensitivity: | 0.107ng/mL |
| Type: | Traditional GLS ELISA kit |
| Synonyms: | GLS1; Glutaminase kidney isoform, mitochondrial; K-glutaminase; L-glutamine amidohydrolase |
| Species: | Rat |
| Sample type: | serum, plasma, tissue homogenates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 24398 |
| UniProt ID: | P13264 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Enables several functions, including anion binding activity; dynein light chain binding activity; and metal ion binding activity. Involved in glutamine metabolic process; positive regulation of cell communication; and positive regulation of epithelial cell proliferation. Located in axon terminus; myelin sheath; and perikaryon. Part of protein-containing complex. Used to study epilepsy; obesity; and temporal lobe epilepsy. Biomarker of diabetic retinopathy; middle cerebral artery infarction; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in congenital glutamine deficiency; epilepsy (multiple); heart disease; and neurodegenerative disease (multiple). Orthologous to human GLUL (glutamate-ammonia ligase).
