serum, plasma, tissue homogenates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
24451
UniProt ID:
P06762
Component:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables several functions, including heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and phospholipase D activity. Involved in several processes, including intracellular signal transduction; negative regulation of apoptotic process; and regulation of gene expression. Located in caveola; endoplasmic reticulum; and nucleus. Used to study several diseases, including artery disease (multiple); cerebrovascular disease (multiple); hepatic vascular disease (multiple); limb ischemia; and sciatic neuropathy. Biomarker of several diseases, including Sjogren's syndrome; artery disease (multiple); brain disease (multiple); liver disease (multiple); and lung disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); cerebrovascular disease (multiple); factor VIII deficiency; lung disease (multiple); and type 2 diabetes mellitus. Orthologous to human HMOX1 (heme oxygenase 1).
