1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Predicted to enable BMP binding activity; coreceptor activity; and transferrin receptor binding activity. Predicted to contribute to BMP receptor activity. Predicted to be involved in several processes, including negative regulation of transcription by RNA polymerase II; protein autoprocessing; and transforming growth factor beta receptor superfamily signaling pathway. Predicted to act upstream of or within multicellular organismal-level iron ion homeostasis; negative regulation of BMP signaling pathway; and positive regulation of transcription by RNA polymerase II. Located in basolateral plasma membrane. Human ortholog(s) of this gene implicated in hemochromatosis and hemochromatosis type 2A. Orthologous to human HJV (hemojuvelin BMP co-receptor).
