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Nphs2
| Detection range: | 0.156-10ng/mL |
| Sensitivity: | 0.053ng/mL |
| Type: | Traditional PDCN ELISA kit |
| Synonyms: | NPHS2; NPHS-2; Nephrosis 2; Idiopathic Steroid-Resistant |
| Species: | Rat |
| Sample type: | urine, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 170672 |
| UniProt ID: | Q8K4G9 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Predicted to be involved in actin cytoskeleton organization and metanephric podocyte development. Predicted to act upstream of or within gene expression. Predicted to be located in cytoplasmic side of plasma membrane; membrane raft; and slit diaphragm. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. Used to study membranous glomerulonephritis and proteinuria. Biomarker of nephrotic syndrome. Human ortholog(s) of this gene implicated in nephrotic syndrome type 2. Orthologous to human NPHS2 (NPHS2 stomatin family member, podocin).
