CD140a; PDGFR2; Rhe-PDGFRA; CD140 antigen-like family member A; Platelet-derived growth factor receptor 2; Alpha-type platelet-derived growth factor receptor
Species:
Rat
Sample type:
tissue homogenates, cell lysates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
25267
UniProt ID:
P20786
Component:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables phosphatidylinositol 3-kinase binding activity and platelet-derived growth factor alpha-receptor activity. Involved in several processes, including cellular response to interleukin-1; lung growth; and positive regulation of branching involved in lung morphogenesis. Located in several cellular components, including axon; nucleus; and plasma membrane. Used to study middle cerebral artery infarction. Biomarker of chronic ulcer of skin; hypertension; oligohydramnios; pulmonary fibrosis; and sciatic neuropathy. Human ortholog(s) of this gene implicated in hematologic cancer (multiple); hypereosinophilic syndrome; and pancreatic cancer. Orthologous to human PDGFRA (platelet derived growth factor receptor alpha).
