Sidebar
Phb1
| Detection range: | 0.312-20ng/mL |
| Sensitivity: | 0.121ng/mL |
| Type: | Traditional PHB ELISA kit |
| Synonyms: | Prohibitin; PHB |
| Species: | Rat |
| Sample type: | serum, plasma or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 25344 |
| UniProt ID: | P67779 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Predicted to enable several functions, including complement binding activity; histone deacetylase binding activity; and protein heterodimerization activity. Involved in several processes, including female gonad development; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and positive regulation of smooth muscle cell proliferation. Located in mitochondrial outer membrane. Is active in GABA-ergic synapse; glutamatergic synapse; and postsynaptic density. Is extrinsic component of presynaptic active zone membrane. Biomarker of urinary bladder cancer. Human ortholog(s) of this gene implicated in breast cancer and sporadic breast cancer. Orthologous to human PHB1 (prohibitin 1).
