RIP3; RIP-like protein kinase 3; Receptor-interacting protein 3
Species:
Rat
Sample type:
tissue homogenates, cell lysates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
246240
UniProt ID:
Q9Z2P5
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables death receptor binding activity. Involved in positive regulation of necroptotic process; positive regulation of neuron apoptotic process; and positive regulation of non-canonical NF-kappaB signal transduction. Part of protein-containing complex. Used to study epilepsy. Human ortholog(s) of this gene implicated in immunodeficiency 57. Orthologous to human RIPK1 (receptor interacting serine/threonine kinase 1).
