| Detection range: | 62.5-4000pg/mL |
| Sensitivity: | 25.3pg/mL |
| Type: | Traditional SOD2 ELISA kit |
| Synonyms: | IPO-B; MNSOD; Mn-SOD |
| Species: | Rat |
| Sample type: | serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 24787 |
| UniProt ID: | P07895 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Enables copper ion binding activity; protein phosphatase 2B binding activity; and superoxide dismutase activity. Involved in several processes, including hydrogen peroxide biosynthetic process; removal of superoxide radicals; and response to antipsychotic drug. Located in several cellular components, including dense core granule; neuronal cell body; and peroxisome. Part of protein-containing complex. Used to study hyperthyroidism; hypothyroidism; middle cerebral artery infarction; and sciatic neuropathy. Biomarker of several diseases, including alcohol use disorder; artery disease (multiple); congenital diaphragmatic hernia; metabolic dysfunction-associated steatohepatitis; and middle cerebral artery infarction. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; artery disease (multiple); eye disease (multiple); glucose metabolism disease (multiple); and neurodegenerative disease (multiple). Orthologous to human SOD1 (superoxide dismutase 1).
