Sidebar
Ac-DEVD-CHO is a synthetic tetrapeptide that acts as a competitive inhibitor of caspase-3 and caspase-7. It contains the amino acid sequence corresponding to the PARP cleavage site. Ac-DEVD-CHO is commonly used to inhibit caspase-3/7 activity in apoptotic cells and to investigate events downstream of caspase-3/7 activation.
Specifications
1. Substrate name: Ac-DEVD-CHO
2. Molecular weight: 502.5
3. Peptide sequence: DEVD
4. Useful to inhibit: Caspase-3, -7
Applications
Assay of caspase activity
Component
1. Ac-DEVD-CHO: 5 mg
Storage
Store at -20°C
