1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) is a neutral phospholipid containing 18:1 fatty acid chains at the sn-1 and sn-2 positions. The compound is sensitive to pH changes: under acidic conditions, it adopts an inverted hexagonal micelle structure, whereas under alkaline conditions, it transforms into spherical micelles. DOPE can serve as an emulsifier to facilitate the transport of DNA–liposome complexes across biological membranes. It is often used in combination with cationic phospholipids to enhance transfection efficiency in DNA transfection studies, serving as a non-viral method of gene delivery.
Specifications
1. CAS Number: 4004-05-1
3. Molecular Formula: C41H78NO8P
4. Purity: >99%
5. Molecular Weight: 744.1
Component
1. DOPE: 500 mg
Storage
Store at -20°C
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